DISEASES

Disease-gene associations mined from literature

Literature on HASPIN

HASPIN [ENSP00000325290]

Serine/threonine-protein kinase haspin; Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. May act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle. ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:17084365,

Synonyms:  HASPIN,  Q8TF76,  Q8TF76p,  hQ8TF76,  2VUW ...

Linkouts:  STRING  Pharos  UniProt  OMIM