Literature on GGA2
GGA2 [ENSP00000311962]
ADP-ribosylation factor-binding protein GGA2; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif . Mediates export of the GPCR receptor ADRA2B to the cell surface . Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans- Golgi network .
Synonyms: GGA2, GGA2p, hGGA2, H3BMM6, H3BMN6 ...