DISEASES

Disease-gene associations mined from literature

Literature on DENND6A

DENND6A [ENSP00000311401]

Protein DENND6A; Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes; Belongs to the DENND6 family.

Synonyms:  DENND6A,  DENND6Ap,  hDENND6A,  H7C598,  H7C5D0 ...

Linkouts:  STRING  Pharos  UniProt