DISEASES

Disease-gene associations mined from literature

Literature on RNFT1

RNFT1 [ENSP00000304670]

E3 ubiquitin-protein ligase RNFT1; E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis.

Synonyms:  RNFT1,  RNFT1p,  hRNFT1,  E9PI44,  H0YEZ8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM