DISEASES

Disease-gene associations mined from literature

Literature on SPIDR

SPIDR [ENSP00000297423]

DNA repair-scaffolding protein; Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity.

Synonyms:  SPIDR,  B3KP42,  B4DMX9,  E5RFY2,  E5RGV8 ...

Linkouts:  STRING  Pharos  UniProt