DISEASES

Disease-gene associations mined from literature

Literature on CCT8

CCT8 [ENSP00000286788]

T-complex protein 1 subunit theta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis . The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance . As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia . The TRiC complex plays a role in the folding of actin and tubulin (Probable).

Synonyms:  CCT8,  CCT8p,  hCCT8,  H7C2U0,  H7C4C8 ...

Linkouts:  STRING  Pharos  UniProt