DISEASES

Disease-gene associations mined from literature

Literature on PLEKHH2

PLEKHH2 [ENSP00000282406]

Pleckstrin homology domain-containing family H member 2; In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia.

Synonyms:  PLEKHH2,  PLEKHH2p,  hPLEKHH2,  E5RGK1,  H0YBV1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM