DISEASES

Disease-gene associations mined from literature

Literature on KYAT3

KYAT3 [ENSP00000260508]

Kynurenine--oxoglutarate transaminase 3; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se-conjugates of L- (seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity). Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro) (By similarity).

Synonyms:  KYAT3,  KYAT3p,  hKYAT3,  A0A0A0MRN7,  B4DW13 ...

Linkouts:  STRING  Pharos  UniProt  OMIM