DISEASES

Disease-gene associations mined from literature

Literature on AHSA1

AHSA1 [ENSP00000216479]

Activator of 90 kDa heat shock protein ATPase homolog 1; Acts as a co-chaperone of HSP90AA1 . Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity . Competes with the inhibitory co- chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins . Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins .

Synonyms:  AHSA1,  AHSA1p,  hAHSA1,  G3V3W9,  G3V438 ...

Linkouts:  STRING  Pharos  UniProt  OMIM