DISEASES

Disease-gene associations mined from literature

Literature on G2E3

G2E3 [ENSP00000206595]

G2/M phase-specific E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.

Synonyms:  G2E3,  G2E3p,  hG2E3,  A0A3B3ISH7,  F5GX24 ...

Linkouts:  STRING  Pharos  UniProt  OMIM