DISEASES

Disease-gene associations mined from literature

Literature on SULT1B1

SULT1B1 [ENSP00000308770]

Sulfotransferase family cytosolic 1B member 1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine, reverse triiodothyronine and thyroxine.

Synonyms:  SULT1B1,  SULT1B1p,  hSULT1B1,  D6RD70,  D6RIA8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM