DISEASES

Disease-gene associations mined from literature

Literature on UGGT2

UGGT2 [ENSP00000365938]

UDP-glucose:glycoprotein glucosyltransferase 2; Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. ; Belongs to the glycosyltransferase 8 family.

Synonyms:  UGGT2,  UGGT2p,  hUGGT2,  A0A087WYR2,  A0A1W2PQ18 ...

Linkouts:  STRING  Pharos  UniProt  OMIM