DISEASES

Disease-gene associations mined from literature

Literature on CEP72

CEP72 [ENSP00000264935]

Centrosomal protein of 72 kDa; Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs) . Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 .

Synonyms:  CEP72,  CEP72p,  hCEP72,  Q9P209,  Q9P209p ...

Linkouts:  STRING  Pharos  UniProt