Literature on TMEM97
TMEM97 [ENSP00000226230]
Sigma intracellular receptor 2; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cancer cells . Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation . Under investigation for its potential diagnostic and therapeutic uses . May play a role as a regulator of cellular cholesterol homeostasis . May function as sterol isomerase . May alter the activity of some cytochrome P450 proteins . ECO:0000303|PubMed:22292588, ECO:0000303|PubMed:23922215,
Synonyms: TMEM97, TMEM97p, hTMEM97, J3KT68, J3KTD1 ...