DISEASES

Disease-gene associations mined from literature

Literature on ASH1L

ASH1L [ENSP00000376204]

Histone-lysine N-methyltransferase ASH1L; Histone methyltransferase specifically trimethylating 'Lys- 36' of histone H3 forming H3K36me3 . Also monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro (By similarity). The physiological significance of the H3K9me1 activity is unclear (By similarity); Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.

Synonyms:  ASH1L,  ASH1Lp,  hASH1L,  F8VWK7,  H0YI82 ...

Linkouts:  STRING  Pharos  UniProt  OMIM