DISEASES

Disease-gene associations mined from literature

Literature on NCS1

NCS1 [ENSP00000361475]

Neuronal calcium sensor 1; Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage- gated calcium channel (By similarity); Belongs to the recoverin family.

Synonyms:  NCS1,  NCS1p,  hNCS1,  A0A024R8B2,  FREQ ...

Linkouts:  STRING  Pharos  UniProt  OMIM