DISEASES

Disease-gene associations mined from literature

Literature on ENTPD4

ENTPD4 [ENSP00000351520]

Ectonucleoside triphosphate diphosphohydrolase 4; Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP, AMP, ADP, ATP and UMP are not substrates. Preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP; Belongs to the GDA1/CD39 NTPase family.

Synonyms:  ENTPD4,  ENTPD4p,  hENTPD4,  E5RIB2,  H0YAN2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM