DISEASES

Disease-gene associations mined from literature

Literature on HDAC11

HDAC11 [ENSP00000295757]

Histone deacetylase 11; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Synonyms:  HDAC11,  HDAC11p,  hHDAC11,  A0A024R2I1,  B5MC52 ...

Linkouts:  STRING  Pharos  UniProt  OMIM