DISEASES

Disease-gene associations mined from literature

Literature on DNAJC27

DNAJC27 [ENSP00000264711]

DnaJ homolog subfamily C member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.

Synonyms:  DNAJC27,  DNAJC27p,  hDNAJC27,  Q9NZQ0,  Q9NZQ0p ...

Linkouts:  STRING  Pharos  UniProt  OMIM