DISEASES

Disease-gene associations mined from literature

Literature on RAB22A

RAB22A [ENSP00000244040]

Ras-related protein Rab-22A; Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes . Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth . Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form . ; Belongs to the small GTPase superfamily. Rab family.

Synonyms:  RAB22A,  RAB22Ap,  hRAB22A,  Q9UL26,  Q9UL26p ...

Linkouts:  STRING  Pharos  UniProt  OMIM