DISEASES

Disease-gene associations mined from literature

Literature on C5

C5 [ENSP00000223642]

Complement C5 alpha' chain; Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.

Synonyms:  C5,  C5p,  hC5,  P01031,  P01031p ...

Linkouts:  STRING  Pharos  UniProt  OMIM