DISEASES

Disease-gene associations mined from literature

Literature on NECAB2

NECAB2 [ENSP00000307449]

N-terminal EF-hand calcium-binding protein 2; May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation.

Synonyms:  NECAB2,  NECAB2p,  hNECAB2,  H3BPH6,  H3BQC7 ...

Linkouts:  STRING  Pharos  UniProt