DISEASES

Disease-gene associations mined from literature

Literature on EID3

EID3 [ENSP00000435619]

EP300-interacting inhibitor of differentiation 3; Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double- strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components; Belongs to the NSE4 family.

Synonyms:  EID3,  EID3p,  hEID3,  A0A140VJI9,  Q8N140 ...

Linkouts:  STRING  Pharos  UniProt