DISEASES

Disease-gene associations mined from literature

Literature on PARD6B

PARD6B [ENSP00000360672]

Partitioning defective 6 homolog beta; Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins; Belongs to the PAR6 family.

Synonyms:  PARD6B,  PARD6Bp,  hPARD6B,  Q9BYG5,  Q9BYG5p ...

Linkouts:  STRING  Pharos  UniProt  OMIM