DISEASES

Disease-gene associations mined from literature

Literature on QSOX1

QSOX1 [ENSP00000356574]

Sulfhydryl oxidase 1; Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide (PubMed:17331072, PubMed:18393449, PubMed:23704371, PubMed:30367560, PubMed:23867277). Plays a role in disulfide bond formation in a variety of extracellular proteins (PubMed:17331072, PubMed:30367560, PubMed:22801504, PubMed:23867277). In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration . ECO:0000269|PubMed:22801504, ECO:0000269|PubMed:23704371,

Synonyms:  QSOX1,  QSOX1p,  hQSOX1,  A0A140VKE5,  A8MXT8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM