DISEASES

Disease-gene associations mined from literature

Literature on KDM4D

KDM4D [ENSP00000334181]

Lysine-specific demethylase 4D; Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys- 20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Synonyms:  KDM4D,  KDM4Dp,  hKDM4D,  Q6B0I6,  Q6B0I6p ...

Linkouts:  STRING  Pharos  UniProt  OMIM