DISEASES

Disease-gene associations mined from literature

Literature on GPD1L

GPD1L [ENSP00000282541]

Glycerol-3-phosphate dehydrogenase 1-like protein; Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3- phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Synonyms:  GPD1L,  GPD1Lp,  hGPD1L,  C9JFA7,  C9JM46 ...

Linkouts:  STRING  Pharos  UniProt  OMIM