DISEASES

Disease-gene associations mined from literature

Literature on OBI1

OBI1 [ENSP00000282003]

ORC ubiquitin ligase 1; E3 ubiquitin ligase essential for DNA replication origin activation during S phase . Acts as a replication origin selector which selects the origins to be fired and catalyzes the multi-mono-ubiquitination of a subset of chromatin-bound ORC3 and ORC5 during S-phase .

Synonyms:  OBI1,  OBI1p,  hOBI1,  Q5W0B1,  Q5W0B1p ...

Linkouts:  STRING  Pharos  UniProt