DISEASES

Disease-gene associations mined from literature

Literature on MGLL

MGLL [ENSP00000265052]

Monoglyceride lipase; Converts monoacylglycerides to free fatty acids and glycerol (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). Hydrolyzes the endocannabinoid 2- arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth . ECO:0000269|PubMed:20079333, ECO:0000269|PubMed:21049984,; Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family.

Synonyms:  MGLL,  A0A0C4DFN3,  A0A3B3ITT3,  C9J8Q3,  C9JAM4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM