DISEASES

Disease-gene associations mined from literature

Literature on FAIM2

FAIM2 [ENSP00000321951]

Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas- induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. ; Belongs to the BI1 family. LFG subfamily.

Synonyms:  FAIM2,  FAIM2p,  hFAIM2,  A0A0A0MTP9,  F8VV65 ...

Linkouts:  STRING  Pharos  UniProt  OMIM