DISEASES

Disease-gene associations mined from literature

Literature on EIF4E

EIF4E [ENSP00000425561]

Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.

Synonyms:  EIF4E,  EIF4Ep,  hEIF4E,  D6RBW1,  D6RFJ3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM