Literature on ILRUN
ILRUN [ENSP00000363135]
Protein ILRUN; Negative regulator of innate antiviral response. Blocks IRF3- dependent cytokine production such as IFNA, IFNB and TNF . Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP .
Synonyms: ILRUN, A0A024RCW2, C6orf106, Q5TH58, Q9H6K1 ...