DISEASES

Disease-gene associations mined from literature

Literature on CYP4X1

CYP4X1 [ENSP00000360968]

Cytochrome P450 4X1; A cytochrome P450 monooxygenase that selectively catalyzes the epoxidation of the last double bond of the arachidonoyl moiety of anandamide, potentially modulating endocannabinoid signaling. Has no hydroxylase activity toward various fatty acids, steroids and prostaglandins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).

Synonyms:  CYP4X1,  CYP4X1p,  hCYP4X1,  Q8N118,  Q8N118p ...

Linkouts:  STRING  Pharos  UniProt  OMIM