DISEASES

Disease-gene associations mined from literature

Literature on SMC2

SMC2 [ENSP00000286398]

Structural maintenance of chromosomes protein 2; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases; Belongs to the SMC family. SMC2 subfamily.

Synonyms:  SMC2,  SMC2p,  hSMC2,  A0A024R158,  A0A0C4DGE5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM