DISEASES

Disease-gene associations mined from literature

Literature on GDPD3

GDPD3 [ENSP00000384363]

Lysophospholipase D GDPD3; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) and lysophosphatidylcholine (lyso-PC), and to a lesser extent for lysophosphatidylethanolamine (lyso-PE). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine.

Synonyms:  GDPD3,  GDPD3p,  hGDPD3,  H3BMN9,  H3BPX3 ...

Linkouts:  STRING  Pharos  UniProt