DISEASES

Disease-gene associations mined from literature

Literature on MZB1

MZB1 [ENSP00000303920]

Marginal zone B- and B1-cell-specific protein; Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B- cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation; Belongs to the MZB1 family.

Synonyms:  MZB1,  MZB1p,  hMZB1,  D6RII0,  H0Y9L3 ...

Linkouts:  STRING  Pharos  UniProt