DISEASES

Disease-gene associations mined from literature

Literature on SLC1A5

SLC1A5 [ENSP00000444408]

Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids (PubMed:8702519, PubMed:29872227). Through binding of the fusogenic protein syncytin- 1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development . (Microbial infection) Acts as a cell surface receptor for Baboon M7 endogenous virus.

Synonyms:  SLC1A5,  SLC1A5p,  hSLC1A5,  M0QX44,  M0QXM4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM