DISEASES

Disease-gene associations mined from literature

Literature on E2F5

E2F5 [ENSP00000398124]

Transcription factor E2F5; Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis. ; Belongs to the E2F/DP family.

Synonyms:  E2F5,  E2F5p,  hE2F5,  C9JYE9,  E5RHD4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM