DISEASES

Disease-gene associations mined from literature

Literature on NCL

NCL [ENSP00000318195]

Nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG- 3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats.

Synonyms:  NCL,  A0A024R4A0,  C9J1H7,  C9JLB1,  C9JWL1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM