DISEASES

Disease-gene associations mined from literature

Literature on EEF2

EEF2 [ENSP00000307940]

Elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

Synonyms:  EEF2,  EEF2p,  hEEF2,  A0A384N6H1,  M0R0I6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM