DISEASES

Disease-gene associations mined from literature

Literature on H2AW

H2AW [ENSP00000355656]

Histone H2A type 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms:  H2AW,  H2AWp,  hH2AW,  HIST3H2A,  Q7L7L0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM