DISEASES

Disease-gene associations mined from literature

Literature on HAS3

HAS3 [ENSP00000304440]

Hyaluronan synthase 3; Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction (By similarity); Belongs to the NodC/HAS family.

Synonyms:  HAS3,  HAS3p,  hHAS3,  H3BRH5,  O00219 ...

Linkouts:  STRING  Pharos  UniProt  OMIM