DISEASES

Disease-gene associations mined from literature

Literature on PCDH12

PCDH12 [ENSP00000231484]

Protocadherin-12, secreted form; Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions (By similarity). Acts as a regulator of cell migration, probably via increasing cell- cell adhesion . Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions (By similarity). Unable to bind to catenins, weakly associates with the cytoskeleton (By similarity).

Synonyms:  PCDH12,  PCDH12p,  hPCDH12,  E5RJD4,  Q9NPG4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM