DISEASES

Disease-gene associations mined from literature

Literature on MORC3

MORC3 [ENSP00000383333]

MORC family CW-type zinc finger protein 3; Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism . Sumoylated MORC3-NBs can also associate with PML-NBs . Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity . Binds RNA in vitro . May be required for influenza A transcription during viral infection .

Synonyms:  MORC3,  MORC3p,  hMORC3,  H0YHQ4,  H0YIR5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM