DISEASES

Disease-gene associations mined from literature

Literature on AGO4

AGO4 [ENSP00000362306]

Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). ; Belongs to the argonaute family. Ago subfamily.

Synonyms:  AGO4,  AGO4p,  hAGO4,  Q9HCK5,  Q9HCK5p ...

Linkouts:  STRING  Pharos  UniProt