DISEASES

Disease-gene associations mined from literature

Literature on SLC22A8

SLC22A8 [ENSP00000337335]

Solute carrier family 22 member 8; Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA). ECO:0000269|PubMed:15644426, ECO:0000269|PubMed:15846473,; Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

Synonyms:  SLC22A8,  SLC22A8p,  hSLC22A8,  H7BXN9,  Q8TCC7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM