DISEASES

Disease-gene associations mined from literature

Literature on ZNF516

ZNF516 [ENSP00000394757]

Zinc finger protein 516; Transcriptional regulator that binds to the promoter and activates the transcription of genes promoting brown adipose tissue (BAT) differentiation. Among brown adipose tissue-specific genes, binds the proximal region of the promoter of the UCP1 gene to activate its transcription and thereby regulate thermogenesis (By similarity). May also play a role in the cellular response to replication stress .

Synonyms:  ZNF516,  ZNF516p,  hZNF516,  A0A087WUJ4,  F5H2K2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM