DISEASES

Disease-gene associations mined from literature

Literature on GNG7

GNG7 [ENSP00000371594]

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity).

Synonyms:  GNG7,  GNG7p,  hGNG7,  K7ESC6,  O60262 ...

Linkouts:  STRING  Pharos  UniProt  OMIM