DISEASES

Disease-gene associations mined from literature

Literature on HABP4

HABP4 [ENSP00000364398]

Intracellular hyaluronan-binding protein 4; RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation (PubMed:14699138, PubMed:16455055, PubMed:19523114, PubMed:21771594). Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity). Plays a role in pre-mRNA splicing regulation . Binds (via C-terminus) to poly(U) RNA . Involved in mRNA translation regulation, probably at the initiation step . Seems to play a role in PML-nuclear bodies formation . ECO:0000269|PubMed:14699138, ECO:0000269|PubMed:16455055, ECO:0000269|PubMed:19523114, ECO:0000269|PubMed:21771594,

Synonyms:  HABP4,  HABP4p,  hHABP4,  Q5JVS0,  Q5JVS0p ...

Linkouts:  STRING  Pharos  UniProt