DISEASES

Disease-gene associations mined from literature

Literature on NRG3

NRG3 [ENSP00000361214]

Pro-neuregulin-3, membrane-bound isoform; Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes. ; Belongs to the neuregulin family.

Synonyms:  NRG3,  NRG3p,  hNRG3,  D9ZHP6,  D9ZHQ3 ...

Linkouts:  STRING  Pharos  UniProt  OMIM